Octa-1,7-diene-4,5-diamine Derivatives: Useful Intermediates for the Stereoselective Synthesis of Nitrogen Heterocycles and Ligands for Asymmetric Catalysis

Autor:	Stefano Grilli, Diego Savoia, Andrea Gualandi
Rok vydání:	2016
Předmět:	Allylic rearrangement Diene 010405 organic chemistry Organic Chemistry Enantioselective synthesis 010402 general chemistry 01 natural sciences 0104 chemical sciences Stereocenter chemistry.chemical_compound chemistry Diamine Organic chemistry Glyoxal Stereoselectivity Physical and Theoretical Chemistry Carbene
Zdroj:	European Journal of Organic Chemistry. 2016:3143-3156
ISSN:	1434-193X
Popis:	The octa-1,7-diene-4,5-diamine skeleton is usually prepared by the addition of allylic organometallic reagents to glyoxal diimines. The relative and absolute configurations of the C4 and C5 stereocenters are dependent on the nature of the (chiral) nitrogen substituents. These compounds are useful intermediates for the construction of NHC carbene complexes and nitrogen heterocycles, such as 2,2′-bipyrrolidines, 2,5-diazabicyclo[2.2.1]heptanes, amino- and hydroxy-substituted 7-azanorbornane, and diamino-substituted cyclohexanols and cyclohexanediols.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::4d7b68fc42189f94b8e8d1dd10a560a1 https://doi.org/10.1002/ejoc.201600310 Zobrazit plný text záznamu Plný text ve formátu PDF Plný text ve formátu HTML
Nepřihlášeným uživatelům se plný text nezobrazuje	K zobrazení výsledku je třeba se přihlásit.