Laser nephelometry and radial immunodiffusion compared for immunoglobulin quantification in pathological sera

Autor:	A. Francina, H. Cloppet, H Coquelin, Creyssel R, P. Hutinel, Y. Boucaud-Maitre
Rok vydání:	1982
Předmět:	Laser nephelometry Radial immunodiffusion Chromatography Nephelometer biology Chemistry Biochemistry (medical) Clinical Biochemistry Mean value Immunoglobulin class biology.protein Cellulose acetate electrophoresis Antibody Nephelometry
Zdroj:	Clinical Chemistry. 28:180-182
ISSN:	1530-8561 0009-9147
DOI:	10.1093/clinchem/28.1.180
Popis:	We evaluated nephelometers from Behring, Hyland, and Beckman for IgG, IgA, and IgM quantitation in sera from patients with monoclonal gammopathies. The intra-batch precision of each instrument for each immunoglobulin class and for different concentrations of the same immunoglobulin was compared to the one obtained with the radial immunodiffusion method. No nephelometer showed a clearly better precision. The correlation with cellulose acetate electrophoresis was good for each of the three nephelometers. The mean value by the radial immunodiffusion method was higher than corresponding determinations by nephelometry.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::4d73999c432040c8dc709508ccaf71a7 https://doi.org/10.1093/clinchem/28.1.180 Zobrazit plný text záznamu