Effects of low environmental temperature on the breeding performance of mice
| Autor: | S. A. Barnett, Brenda M. Manly |
|---|---|
| Rok vydání: | 1959 |
| Předmět: | |
| Zdroj: | Proceedings of the Royal Society of London. Series B. Biological Sciences. 151:87-105 |
| ISSN: | 2053-9193 0080-4649 |
| DOI: | 10.1098/rspb.1959.0052 |
| Popis: | Mice of strainsA,A2GandC57BLhave been bred to the age of 28 weeks at three temperatures: 21 °C (controls), 10 °C and ─ 3 °C.Breedingat21 °C. In the control temperature theC57BLmice bore more young per pair than either of theAstrains, but a higher mortality in the nest gave them a yield of young weaned at 3 weeks similar to that of theAstrains. Body weights ofC57BLyoung at 3 weeks were lower than those of theAstrains.Breeding at10 °C. In the intermediate temperature mice of strainAhad fewerlittersthan those of the same strain at 21 °C, but otherwise their reproductive performance was unaffected. The reproduction of mice of strainA2Gwas unchanged. TheC57BLmice bore more young per pair, and weaned more young per pair, than theC57BLcontrols. The weights of the 3-week young, of all strains, were hardly different from those of the controls.Breeding at─ 3 °C. In all three strains breeding began later at the low temperature and there was a higher mortality between birth and weaning; consequently, the number of youngweanedper pair was one-third to one-fifth of the control figure. Other parameters of breeding were influenced in different ways in the different strains: in particular, (a) the number of youngbornper pair was little changed in strainA, but substantially reduced in the other two strains; and (b), complete failure to breed owing to the cold occurred only in strainC57BL. The effect of cold on the weights of the weaned young also varied: in the twoAstrains, although there were fewer young per litter, the young were lighter than the controls; of theC57BLyoung, those of the first generation were heavier than the controls, but not significantly so, while those of the second generation were lighter.Litter size.At ─ 3 °C, the number of young born per litter, and weaned per weaned litter, was unaffected in strainA; but both these parameters were reduced in strainsA2GandC57BL. There was no evidence that litter size influenced the body weight of the young at 3 weeks in strainA2Geither at 21 °C or at ─3 °C, or in strainAmice at 21 °C. But there was evidence of decline in body weight with increase in litter size in strainAmice at ─3 °C and inC57BLmice at both temperatures. The number of young per litter tended to decline after the third litters in all three strains at both ─3 and 21 °C.Effects of transfer between temperatures. After 5 generations at ─3 °C, mice of strainsAandA2Gwere transferred to 21 °C at 5 weeks and mated; these ‘reversed’ pairs showed no difference in breeding performance from the controls. The young of theAstrain reversed pairs did not differ in weight at 3 weeks from those of the controls, but those of theA2Greversed pairs were lighter. Some of the offspring of the reversed pairs were transferred back to ─3 °C at 5 weeks and mated; the number of litters born to these ‘doubly reversed’ pairs was lower than that of mice indigenous to the cold, but the numbers born and weaned per litter were higher. In strainA, the young of the doubly reversed pairs were heavier than those of pairs indigenous to the cold.Variation. Variation was usually higher in the cold environment than in the warm, especially in those parameters of reproduction which were most affected by the cold. This did not apply to weights at 3 weeks, probably owing to the death of the extreme variants before weaning.General. The mice at ─3 °C were breeding in conditions of continued mild ‘stress’. The main effects on reproduction were the delay in the onset of breeding, the high infant mortality and the greater variation of performance. |
| Databáze: | OpenAIRE |
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