Characterization of Specific Ion Effects on PI(4,5)P2 Clustering: Molecular Dynamics Simulations and Graph-Theoretic Analysis
| Autor: | Richard W. Pastor, Arne Gericke, Kyungreem Han |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
010304 chemical physics
Graph theoretic Colocalization Computational biology 010402 general chemistry 01 natural sciences 0104 chemical sciences Surfaces Coatings and Films Characterization (materials science) Ion Molecular dynamics chemistry.chemical_compound chemistry 0103 physical sciences Materials Chemistry Pi lipids (amino acids peptides and proteins) Phosphatidylinositol Physical and Theoretical Chemistry Cluster analysis |
| Zdroj: | The Journal of Physical Chemistry B. 124:1183-1196 |
| ISSN: | 1520-5207 1520-6106 |
| DOI: | 10.1021/acs.jpcb.9b10951 |
| Popis: | Numerous cellular functions mediated by phosphatidylinositol (4,5)-bisphosphate (PI(4,5)P2; PIP2) involve clustering of the lipid as well as colocalization with other lipids. Although the cation-me... |
| Databáze: | OpenAIRE |
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