Chronisches, therapieresistentes Ulkus am Ringfinger
| Autor: | N. S. Häring, Robert Strohal, F. Offner, S. Dertinger |
|---|---|
| Rok vydání: | 2017 |
| Předmět: |
0301 basic medicine
Pathology medicine.medical_specialty Soft Tissue Neoplasm medicine.diagnostic_test business.industry medicine.medical_treatment Epithelioid sarcoma Soft tissue sarcoma Dermatology Skin ulcer Sentinel node medicine.disease Radiation therapy 03 medical and health sciences 030104 developmental biology 0302 clinical medicine 030220 oncology & carcinogenesis Biopsy medicine Sarcoma medicine.symptom business |
| Zdroj: | Der Hautarzt. 69:408-412 |
| ISSN: | 1432-1173 0017-8470 |
| DOI: | 10.1007/s00105-017-4087-0 |
| Popis: | The epithelioid sarcoma classic, "distal" type was first published in 1970. It is a very rare, malignant, aggressive subcutaneous soft tissue sarcoma that shows characteristic positivity for both epithelial and mesenchymal immunohistochemical markers. It grows very slowly and mostly presents in young men. Clinically the tumor is characterized as a coarse cutaneous or subcutaneous nodular induration that often ulcerates in the course of the disease. An association with trauma is often described and can lengthen time to diagnosis. Most frequently it is found on the flexural side of fingers, the back of the hands, soles of the feet, and extensor sides of arms and legs. Specific for this type of sarcoma is the progression along nerves, tendons, and fasciae. Treatment of choice should be wide excision of the tumor, sentinel node biopsy, and possibly even localized postoperative radiation therapy. Unfortunately the epithelioid sarcoma is very likely to recur and is then associated with metastases in the lung and lymph nodes. |
| Databáze: | OpenAIRE |
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