ChemInform Abstract: Synthesis and Resolution of β-(Aminomethyl)-4- chlorobenzeneethanesulfinic Acid - a Potent GABAB Receptor Ligand

Autor:	Shing-Chun Wong, Ho-Jane Shue, Spitler James M, David J. Blythin, Xiao Chen, Carruthers Nicholas I, Stanley Mittelman
Rok vydání:	2010
Předmět:	chemistry.chemical_compound nervous system Chemistry Stereochemistry Resolution (electron density) Antagonist Saclofen General Medicine GABAB receptor Enantiomer Ligand (biochemistry)
Zdroj:	ChemInform. 26
ISSN:	0931-7597
Popis:	The synthesis and resolution of β-(Aminomethyl)-4-chlorobenzeneethanesulfinic acid together with the GABAB receptor affinity for the racemate and enantiomers is described. In addition the synthesis and GABAB receptor affinity of the enantiomers of the known GABAB antagonist (Saclofen) is reported for the first time
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::4d5a52d7f2529e6af11a552092117c30 https://doi.org/10.1002/chin.199527107 Zobrazit plný text záznamu Plný text