Carbonylation with CO2 and Phosphorus Electrophiles: A Convenient Method for the Synthesis of 2-Oxazolidinones from 1,2-Amino Alcohols

Autor: Jairo Paz, Carlos Pérez-Balado, Beatriz Iglesias, Luis Muñoz
Rok vydání: 2009
Předmět:
Zdroj: Synlett. 2009:395-398
ISSN: 1437-2096
0936-5214
DOI: 10.1055/s-0028-1087531
Popis: 2-Oxazolidinones were prepared in good yields from 1,2-amino alcohols and CO 2 in the presence of tetramethyl-phenylguanidine (PhTMG) as a base and a variety of phosphorus electrophiles under mild conditions. This procedure is advantageous over previous methodologies and relies on a novel carbonylation procedure that utilizes nontoxic CO 2 and phosphorus electrophiles.
Databáze: OpenAIRE