Coordination of phases of solar activity and of monthly rhythms of blood serum cholesterol levels in rabbits

Autor: V. V. Nemov, M. M. Avramenko, O. A. Nechitailo, E. N. Chirkova
Rok vydání: 1988
Předmět:
Zdroj: Bulletin of Experimental Biology and Medicine. 105:403-408
ISSN: 1573-8221
0007-4888
DOI: 10.1007/bf00835764
Popis: Changes in the serum cholesterol concentration constitute a complex oscillatory process [14]. Besides circadian fluctuations [9], distinct seasonal fluctuations of this Parameter also are observed [I0, ll]. Natural fluctuations of the blood cholesterol concentration in experimental animals make interpretation of the data difficult when the influence of various factors on cholesterol metabolism is investigated, for there is as yet no substantiated approach to the prediction of oscillations of the blood cholesterol level during the course of a chronic experiment. On the basis of data of helio-biology [12] we postulated that such prediction is possible if correlation can be established between the phases of the monthly cholesterol biorhythms and monthly rhythms of change of a concrete parameter of solar activity. However, hecause of the difficulty of conducting long-term biological investigations and because of the absence of any single mathematical approach, parameters of the basic cholesterol biorhythms of varied frequency have not yet been discovered, nor has their possible correlation between rhythms of solar activity been established. The solution to this problem is essential for the creation of a reliable dynamic background against which it will be possible to judge changes in the blood cholesterol level of rabbits in model investigations to study the pathogenesis of atherosclerosis.
Databáze: OpenAIRE
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