Zinc uptake in swine intestinal brush border membrane vesicles using a 65Zn/69mZn duel isotope experiment
| Autor: | J. S. Morris, T. L. Veum, C. E. Huntington |
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| Rok vydání: | 2007 |
| Předmět: |
Chromatography
Isotope Brush border Chemistry Health Toxicology and Mutagenesis Vesicle Public Health Environmental and Occupational Health chemistry.chemical_element Nursery pig Zinc Pollution Analytical Chemistry Nuclear Energy and Engineering Radiology Nuclear Medicine and imaging Zinc uptake Digestion Spectroscopy Zinc Supplements |
| Zdroj: | Journal of Radioanalytical and Nuclear Chemistry. 276:129-134 |
| ISSN: | 1588-2780 0236-5731 |
| Popis: | Supplemental zinc as ZnO is routinely added to nursery pig diets at 15 to 20 times the nutritional requirement to alleviate physiological stress and enhance performance. The mechanism by which Zn accomplishes this function is unknown, however, high concentrations of Zn are excreted in the environment at undesirable levels. To study Zn uptake, we developed a multi-stage digestion model followed by exposure to swine intestinal brush border membrane vesicles (BBMV). We report on the feasibility of using a duel label (65Zn and 69mZn) to simultaneously quantify the competitive uptake of Zn from co-existing zinc supplements using our BBMV model. |
| Databáze: | OpenAIRE |
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