Mechanism of the acid-catalyzed hydrolysis of N-acylsulfamates

Autor:	Jean-Baptiste Malaubier, William J. Spillane
Rok vydání:	2007
Předmět:	Hydrolysis Computational chemistry Mechanism (philosophy) Chemistry Acid catalyzed Organic Chemistry Drug Discovery Kinetics Physical chemistry Biochemistry
Zdroj:	Tetrahedron Letters. 48:7574-7577
ISSN:	0040-4039
DOI:	10.1016/j.tetlet.2007.08.107
Popis:	The kinetics of hydrolysis of a series of N-acylsulfamate esters p-XC6H4OSO2NHCOR as models for more complex, biologically important compounds has been examined. Structure-reactivity, solvent-reactivity, thermodynamic data, etc. support a bimolecular mechanism involving water in the transition state (TS).
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::4d34e01290e9ed8fb016736f13980829 https://doi.org/10.1016/j.tetlet.2007.08.107 Zobrazit plný text záznamu Full Text from ScienceDirect