Prediction of osteoporosis severity in patients with rheumatoid arthritis via evaluation of the fetuin-A level

Autor:	E.V. Papichev, B.V. Zavodovsky, Yu.R. Akhverdyan, L.E. Polyakova, Experimental Rheumatology named after A. B. Zborovsky, Ju.V. Polyakova
Rok vydání:	2021
Předmět:	medicine.medical_specialty business.industry Rheumatoid arthritis Internal medicine Osteoporosis Medicine In patient General Medicine business medicine.disease Fetuin Gastroenterology
Zdroj:	Siberian Medical Review. :60-65
ISSN:	2500-0136 1819-9496
DOI:	10.20333/25000136-2021-4-60-65
Popis:	Aim of study. To investigate the level of dependence of osteoporosis (OP) progression severity on the level of fetuin-A (FA) in order to predict the OP progression severity in RA patients. Material and methods. We have examined a total of 110 RA patients (mean age 54.2+11.97). Th e diagnosis was established based on ACR/EULAR criteria 2010. A total of 30 conventionally healthy subjects were enrolled serving as a control group. Evaluation of bone mineral density (BMD) was performed using DXA (Lunar DPX-NT GE densitometer). The FA level was determined through indirect enzyme-linked immunoassay (Human Fetuin-A ELISA test-system). Results. Mean serum FA in healthy subjects amounted to 653.55-972.19μg/ml. We formed 2 groups of RA patients: with blood serum FA levels
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::4d33b20ae3c0c81fa4a2dac857acc388 https://doi.org/10.20333/25000136-2021-4-60-65 Zobrazit plný text záznamu