ChemInform Abstract: Asymmetric C(sp3)-H/C(Ar) Coupling Reactions. Highly enantio-Enriched Indolines via Regiodivergent Reaction of a Racemic Mixture

Autor:	Masafumi Nakanishi, Thomas Buergi, Dmitry Katayev, E. Peter Kuendig
Rok vydání:	2012
Předmět:	inorganic chemicals chemistry.chemical_compound chemistry Racemic mixture General Medicine Methylene Asymmetric induction Medicinal chemistry Coupling reaction
Zdroj:	ChemInform. 43
ISSN:	0931-7597
DOI:	10.1002/chin.201238101
Popis:	The application of bulky chiral ligands (I) in the palladium-catalyzed title reaction of racemic N-aryl, N-alkyl-carbamates (II) results in formation of a mixture of 2-alkyl and 2,3-disubstituted indolines with very high asymmetric induction by either methyl C—H or methylene C—H activation.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::4d32218556463cfd98de12c773dec4e1 https://doi.org/10.1002/chin.201238101 Zobrazit plný text záznamu Plný text