| Autor: |
S. Valdeig, C. Holmer, P. Hoffmann, Kai S. Lehmann, B. B. Frericks, Jerome Ritz, U. Zurbuchen, Andrea Schenk, H. J. Buhr |
| Rok vydání: |
2009 |
| Předmět: |
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| Zdroj: |
Deutsche Gesellschaft für Chirurgie ISBN: 9783642006241 |
| DOI: |
10.1007/978-3-642-00625-8_36 |
| Popis: |
Objective: To evaluate the cooling effect of liver perfusion on the thermal destruction volume of radiofrequency ablation (RFA) ex vivo. Methods: Perfused glass tubes (diameter [mm]/flow [ml/min]: 5/1040, 8/1470, 10/1875) and biploar RFA applicators (diameter: 1.8 mm, electrode length: 30 mm, distance to glass tube: 5/10 mm, internally cooled) were inserted in parallel to each other in pig livers ex vivo. RFA was carried out with 30W and an energy application of 15 kJ. Cooling effects were analyzed by measuring the maximal (Rmax) and minimal radius (Rmin) in digital planimetries of the RFA lesions. Results: There was no difference between Rmax and Rmin between 5 and 10 mm distance of the RFA applicator to the glass tube (11.2±1.4 mm vs. 11.2±1.2 mm, p=0.918). Rmin was reduced to to 4.3±0.6 mm (p≤0.001) at 5 mm distance and 8.4±1.3 (p≤0.001) at 10 mm distance. The cooling effect resulted in RFA lesions with acyclic shapes. No significant differences concerning Rmin were oberved with different flow rates. Conclusions: The cooling effect of simulated liver vessels resulted in acyclic RFA lesions and a decrease in lesion radius. RFA in vicinity to larger liver vessels in vivo can lead to insufficient tumor ablation. Surgical RFA with temporary vessel occlusion should be considered in such situations. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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