Humoral and Cellular Immune Response in Patients with Transitional Cell Carcinoma of the Urinary Bladder (TCC) Against Bladder Carcinoma Cells in Tissue Culture

Autor: S Pauli, Marita Troye, Y. Hansson, H. Blomgren, B. Johansson, M. Karlsson
Rok vydání: 1980
Předmět:
Zdroj: Bladder Tumors and other Topics in Urological Oncology ISBN: 9781461330325
DOI: 10.1007/978-1-4613-3030-1_32
Popis: Non-irradiated and irradiated patients with TCC of the urinary bladder as a group show disease related cytotoxicity. Moreover, our results strongly suggest that the effector cell(s) involved in these allogeneic reactions are of the K-cell type, ie. SIg- and FcR+ lymphocytes acting through antibodies. Furthermore, about 30% of the isolated IgG-fractions from patients sera had ADCC-inducing capacity. By means of using these antibodies in an insolubilised form we are presently trying to identify and characterise the tumour-associated antigens.
Databáze: OpenAIRE