| Autor: | Jeffrey M. Jones, Mary E. Proctor, Bruce S. Klein, Jeffrey P. Davis |
|---|---|
| Rok vydání: | 2002 |
| Předmět: |
Fungal protein
education.field_of_study Pathology medicine.medical_specialty biology business.industry Blastomyces dermatitidis Veterinary (miscellaneous) Incidence (epidemiology) Population Case-control study Outbreak Disease Disease cluster biology.organism_classification Applied Microbiology and Biotechnology Microbiology Medicine business education Agronomy and Crop Science Demography |
| Zdroj: | Mycopathologia. 153:113-120 |
| ISSN: | 0301-486X |
| DOI: | 10.1023/a:1014515230994 |
| Popis: | Much of our understanding of the epidemiologic features of infection with Blastomyces dermatitidis has come from cluster and outbreak investigations which have established the association of human disease with recreational pursuits and the presence of infectious microfoci in areas of moist soil with high organic content. This report describes the clustering of eight cases of pulmonary blastomycosis without an apparent common source exposure which occurred during a 90 day period in a 96 square mile area (population 4,450) within Oconto County, Wisconsin. We conclude that multiple high-risk environmental foci may have existed following a sustained five-year period of diminished precipitation in the cluster area. A case-control study which included family and community controls concluded that multiple earth-disturbing activities engaged in by case-patients was statistically associated with illness. Lymphocyte-proliferation assays of whole blood samples detected previously unrecognized infection withB. dermatitidis among five of 32 family controls. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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