Antibacterial Effects of Sol-Gel Derived Zinc-Containing Hydroxyapatite
| Autor: | Xin Chang Shi, Yun Mao Liao, Hua-zhou Jiang, Wei Li, Jing Xue, Li-ying Xiao, C.Y. Bao |
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| Rok vydání: | 2007 |
| Předmět: |
Materials science
biology Scanning electron microscope Mechanical Engineering Metallurgy Biomaterial chemistry.chemical_element Zinc engineering.material biology.organism_classification Streptococcus mutans Apatite chemistry Coating Mechanics of Materials visual_art visual_art.visual_art_medium engineering General Materials Science Porosity Sol-gel Nuclear chemistry |
| Zdroj: | Key Engineering Materials. :139-142 |
| ISSN: | 1662-9795 |
| Popis: | In order to modify the biological properties of pure hydroxyapatite (HAp), two kinds of zinc-containing HAp, which had zinc content of 5.10wt% and 2.54wt%, respectively, were synthesized via sol-gel technique. The obtained coatings were characterized by X-ray diffraction (XRD) and scanning electron microscope (SEM). Then the antibacterial effects were evaluated through bacteriostatic test on Streptococcus mutans (S.mutans) in vitro and zinc ions releasing ability was investigated through detecting the zinc ions concentration by inductively coupled plasma-atomic emission spectroscopy (ICP-AES). The obtained coatings were observed to possess typical apatite peaks in XRD patterns and high homogeneous and porous surfaces in SEM morphology. The coating layer demonstrated good releasing ability in Brain Heart Infusion (BHI) liquid and obviously inhibitory effects to the growth and proliferation of S. mutans. Based on the results obtained above, it is concluded that the sol-gel derived zinc-containing hydroxyapatite could be applied as an antibacterial effective biomaterial. |
| Databáze: | OpenAIRE |
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