Case series: Hearing loss in neuromyelitis optica spectrum disorders
| Autor: | Haojun Feng, Anna Tomczak, May H. Han, Kristen K. Steenerson, Madina Tugizova |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
Pediatrics
medicine.medical_specialty biology Hearing loss business.industry Multiple sclerosis General Medicine medicine.disease Case review Myelin oligodendrocyte glycoprotein 03 medical and health sciences 0302 clinical medicine Aquaporin 4 Neurology Neuromyelitis Optica Spectrum Disorders otorhinolaryngologic diseases medicine biology.protein Sensorineural hearing loss In patient 030212 general & internal medicine Neurology (clinical) medicine.symptom business 030217 neurology & neurosurgery |
| Zdroj: | Multiple Sclerosis and Related Disorders. 41:102032 |
| ISSN: | 2211-0348 |
| Popis: | Background Aquaporin 4 (AQP4)- and myelin oligodendrocyte glycoprotein (MOG)-associated neuromyelitis optica spectrum disorders (NMOSD) are thought to primarily affect the central nervous system (CNS). However, emerging evidence suggests that there are extra-CNS manifestations of NMOSD, including myopathies, gastrointestinal dysfunction, renal involvement and adverse pregnancy outcomes.1 Methods Three patients who reported hearing loss during a NMOSD relapse were identified through a retrospective case review. Results In this article, we discuss two AQP4-IgG positive NMOSD cases, each presenting with conductive and sensorineural hearing loss, and a case of MOG-IgG-associated NMOSD presenting with sensorineural hearing loss. Conclusion Hearing loss may be present as a relapse in patients with NMOSD. Early recognition and timely treatment are essential to prevent irreversible hearing loss. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Full Text from ScienceDirect