| Autor: | Arne Zibat, You-Ai He, Hans-Peter Klenk, Regina Eiselt, Romy Mueller, Urs A. Meyer, James R. Halpert, Tammy L. Domanski, Elisabeth Hustert, Elena Presecan-Siedel, Ulrich M. Zanger, Jürgen Brockmöller, Leszek Wojnowski, Kishore K. Khan |
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| Rok vydání: | 2001 |
| Předmět: | |
| Zdroj: | Pharmacogenetics. 11:447-458 |
| ISSN: | 0960-314X |
| DOI: | 10.1097/00008571-200107000-00008 |
| Popis: | The genetic component of the inter-individual variability in CYP3A4 activity has been estimated to be between 60% and 90%, but the underlying genetic factors remain largely unknown. A study of 213 Middle and Western European DNA samples resulted in the identification of 18 new CYP3A4 variants, inclu |
| Databáze: | OpenAIRE |
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