| Autor: |
Yong Ho Choi, Chi Hwan Lim, Hyeok Ran Kwon, Kyoung Soo Jang, Luu Hoang Ngoc, Quang Le Dang, Jin-Cheol Kim, Myung Soo Park, Gyung Ja Choi |
| Rok vydání: |
2010 |
| Předmět: |
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| Zdroj: |
Nematology. 12:247-253 |
| ISSN: |
1568-5411 |
| DOI: |
10.1163/138855409x12470480754708 |
| Popis: |
Abstract Methanol extracts of 50 plant species were assessed for nematicidal activity against the pine wood nematode (PWN), Bursaphelenchus xylophilus. Out of these, five extracts: Justicia diclipteroides subsp. usambarica; Nerium oleander; Persea americana; Scadoxus multiflorus subsp. multiflorus; and Thespesia populnea, caused 96-100% mortalities of pine wood nematode at 1000 μg ml–1 for 48 h. Methanol extract of the stem bark of P. americana (avocado) and the n-hexane layer obtained from the methanol extract by solvent partitioning caused 100% mortality of PWN at low concentrations of 125 and 63 μg ml–1, respectively. One potent nematicidal compound was isolated from the stem bark of P. americana and its chemical structure was determined to be isoobtusilactone A (1) by mass and NMR spectral analyses. The chemical showed a very strong nematicidal activity against PWN; it caused mortalities of over 97% at concentrations higher than 50 μg ml–1. Compared with a commercial synthetic nematicide, morantel tartrate, compound 1 showed a little more potent activity. The results suggested that compound 1 may have the potential to be explored as a natural nematicide or be useful as a lead molecule for development of new nematicidal agents for controlling the pine wilt disease caused by B. xylophilus. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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