N-substituted dibutoxyphosphorylacetimidates in phosphorylation reactions

Autor: I. A. Kosheleva, Yu. V. Popov, O. V. Anishchenko, S. M. Ledenev, V. E. Shishkin, M. A. Shevchenko, A. A. Moroz
Rok vydání: 2017
Předmět:
Zdroj: Russian Journal of General Chemistry. 87:2133-2136
ISSN: 1608-3350
1070-3632
DOI: 10.1134/s1070363217090390
Popis: Reaction of N-substituted dibutoxyphosphorylacetimidates with sodium followed by phosphorylation of sodium derivatives with dialkyl chlorophosphates and phenyl dichlorophosphate proceeds selectively under mild conditions to form products of phosphorylation of the methylene group. The synthesized compounds possess potential antisecretory, immunosuppressive, hypolipidemic, and other types of biological activity.
Databáze: OpenAIRE