Hyperglycemia Increases Severity of Staphylococcus aureus Osteomyelitis and Influences Bacterial Genes Required for Survival in Bone

Autor: Casey E. Butrico, Nathan Klopfenstein, Erin R. Green, Joshua R. Johnson, Sun H. Peck, Carolyn B. Ibberson, C. Henrique Serezani, James E. Cassat
Rok vydání: 2023
Předmět:
Zdroj: Infection and Immunity. 91
ISSN: 1098-5522
0019-9567
DOI: 10.1128/iai.00529-22
Popis: Hyperglycemia, or elevated blood glucose, renders individuals more prone to developing severe Staphylococcus aureus infections. S. aureus is the most common etiological agent of musculoskeletal infection, which is a common manifestation of disease in hyperglycemic patients. However, the mechanisms by which S. aureus causes severe musculoskeletal infection during hyperglycemia are incompletely characterized.
Databáze: OpenAIRE