A new synthesis of pulvinic acids
| Autor: | Gerald Pattenden, Neil A. Pegg, Anthony G. Smith |
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| Rok vydání: | 1986 |
| Předmět: | |
| Zdroj: | Tetrahedron Letters. 27:403-406 |
| ISSN: | 0040-4039 |
| DOI: | 10.1016/s0040-4039(00)84030-7 |
| Popis: | Reaction of zinc enolates e.g. (6) derived from arylacetates with 2-aryl-3-methoxymaleic anhydrides e.g. (3) gives intermediates viz (8) which can be dehydrated to Z -and E -isomers of permethylated pulvinic acids; treatment of the latter with trimethylsilyl iodide provides the corresponding pulvinic acids e.g. gomphidic acid (1). |
| Databáze: | OpenAIRE |
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