| Autor: |
Glenn N. Taylor, Charles W. Mays, Walter Angus, David R. Atherton, L. Shabestari, G. B. Thurman |
| Rok vydání: |
1981 |
| Předmět: |
|
| Zdroj: |
Radiation Research. 88:180 |
| ISSN: |
0033-7587 |
| DOI: |
10.2307/3575762 |
| Popis: |
Fourteen osteosarcomas were observed among the eight St. Bernards that died following the injection of239 Pu. Early data tentatively indicate that the St. Bernard is about 5 times more sensitive than the beagle and about 130 times more sensitive than the average person is estimated to be to ${}^{239}{\rm Pu}\text{-induced}$ bone sarcomas. Thus the St. Bernard may be an excellent model in which to study the pathogenesis of bone cancer induction, to evaluate the relationship between spontaneous susceptibility and radiosensitivity, and to determine whether radiosensitivity significantly affects the toxicity ratio of ${}^{239}{\rm Pu}/{}^{226}{\rm Ra}$ . |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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