Stereochemistry in the β-lactam series—III
| Autor: | G. Tsoucaris, C. de Rango, C. Zelwer, R. Parthasarathy, J.L. Luche, Henri B. Kagan |
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| Rok vydání: | 1968 |
| Předmět: |
Stereochemistry
Chemistry Organic Chemistry biochemical phenomena metabolism and nutrition Dihedral angle Ring (chemistry) Biochemistry NMR spectra database chemistry.chemical_compound Crystallography Drug Discovery polycyclic compounds Lactam Valence bond theory Spectral method Cis–trans isomerism Pyramid (geometry) |
| Zdroj: | Tetrahedron. 24:1275-1281 |
| ISSN: | 0040-4020 |
| DOI: | 10.1016/0040-4020(68)88077-9 |
| Popis: | X-ray analysis of β-lactams 5 and 6 confirms the cis configuration assigned before on the basis of their NMR spectra. The valence bonds of nitrogen form a very flat pyramid and the dihedral angle between the Ar 2 phenyl and the β-lactam ring, which is planar, is very small. These results are compared with the data given by spectral methods applied to various β-lactams. |
| Databáze: | OpenAIRE |
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