Influence of magnetic iron oxide nanoparticles on red blood cells and Caco-2 cells

Autor:	Delphine Felder-Flesch, Daniel Moersdorf, Ingolf Bernhardt, Hind Mamlouk-Chaouachi, Geneviève Pourroy, Lai Truonc Phuoc, Pierre Hugounenq, Sylvie Begin-Colin
Rok vydání:	2010
Předmět:	chemistry.chemical_compound chemistry Biochemistry Caco-2 Intracellular pH Biophysics Nanoparticle General Medicine Iron oxide nanoparticles Intracellular
Zdroj:	Advances in Bioscience and Biotechnology. :439-443
ISSN:	2156-8502 2156-8456
Popis:	The interactions of two types of cells (red blood cells, Caco-2 cells) with magnetic iron oxide nanoparticles (non-grafted, citrate-grafted, dendrimer-grafted) of 11 nm in size have been investigated. We focused on two important physiological parameters of the cells, the intracellular pH and the intracellular Ca2+ content. The results show that the nanoparticles do not have a significant influence on the pH and Ca2+ content of Caco-2 cells. The Ca2+ content of red blood cells is also not affected but the intracellular pH is slightly reduced.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::4c7c8e54d6f23cb3c46b791798b25a5a https://doi.org/10.4236/abb.2010.15057 Zobrazit plný text záznamu