Intensity-modulated radiotherapy versus three-dimensional conformal radiotherapy during deep inspiratory breath hold for left-sided whole-breast irradiation: a comparative analysis
| Autor: | G. Moyer, C. Geesey, K. Forbes, Kelli A. Reardon, D. Lain, Krishni Wijesooriya, Daniel M. Trifiletti |
|---|---|
| Rok vydání: | 2015 |
| Předmět: |
medicine.medical_specialty
business.industry medicine.medical_treatment Anterior Descending Coronary Artery medicine.disease Left sided 030218 nuclear medicine & medical imaging Radiation therapy 03 medical and health sciences 0302 clinical medicine Breast cancer Oncology Whole Breast Irradiation Inspiratory breath 030220 oncology & carcinogenesis medicine Radiology Nuclear Medicine and imaging Radiology Intensity modulated radiotherapy Three dimensional conformal radiotherapy business Nuclear medicine |
| Zdroj: | Journal of Radiotherapy in Practice. 15:99-106 |
| ISSN: | 1467-1131 1460-3969 |
| DOI: | 10.1017/s1460396915000394 |
| Popis: | AimDeep inspiratory breath hold (DIBH) during left-breast irradiation helps to minimise cardiac irradiation by physically separating the heart from the left breast. The dose to organs-at-risk in intensity-modulated radiotherapy (IMRT) and opposed tangent three-dimensional conformal radiotherapy (3DCRT) during DIBH in patients with left-sided breast cancer was compared.Materials and methodsA total of 20 consecutive patients with left-sided breast cancer had a computed tomography scan utilising DIBH. Mean volumes of the heart, left anterior descending coronary artery, total lung and right breast receiving 5–95% of the prescription dose were calculated.ResultsTarget volume homogeneity was improved with IMRT and average mean dose to target was higher for 3DCRT (51·03 Gy) compared with IMRT (50·47 Gy, ppppFindingsUnder DIBH, absolute differences between 3DCRT and IMRT were minimal. 3DCRT under DIBH provided excellent dosimetric results in most patients with left-sided breast cancer without the need for IMRT. |
| Databáze: | OpenAIRE |
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