Synthesis of α-hydroxy(polyprenyl) bisphosphonates

Autor:	N. V. Davletshina, O. O. Kolodyazhnaya, S. A. Koshkin, Airat R. Garifzyanov, R. A. Cherkasov, O. I. Kolodyazhnyi
Rok vydání:	2014
Předmět:	Terpene Polyprenol chemistry.chemical_compound chemistry Group (periodic table) Reagent Swern oxidation Organic chemistry Molecule General Chemistry Phosphonate
Zdroj:	Russian Journal of General Chemistry. 84:647-653
ISSN:	1608-3350 1070-3632
DOI:	10.1134/s1070363214040082
Popis:	Bisphosphonates derived from natural terpenes were synthesized by phosphonylation of corresponding aldehydes. The general strategy of introduction of the phosphonate groups into the polyprenol molecule involves successive treatment of a hydroxyl compound by Swern reagent to oxidize the C-OH group into C=O and a (EtO)3P/[PyH]+ClO−4 mixture to phosphylate the resulting carbonyl compound.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::4c53f34c300c3113ad1fe945951c5a19 https://doi.org/10.1134/s1070363214040082 Zobrazit plný text záznamu Plný text ve formátu PDF