MSH/ACTH 4-10 Influences Behavioral and Physiological Measures of Attention1
| Autor: | Jack M. George, Abba J. Kastinj, J. Dennis Nolan, Curt A. Sandman, Jaques Kaswan, Thomas R. McCanne |
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| Rok vydání: | 1977 |
| Předmět: |
endocrine system
medicine.medical_specialty business.industry Pulse (signal processing) Endocrinology Diabetes and Metabolism media_common.quotation_subject Biochemistry (medical) Clinical Biochemistry Biochemistry Endocrinology Perceptual integration Perception Internal medicine Heart rate Medicine business Neuroscience hormones hormone substitutes and hormone antagonists media_common |
| Zdroj: | The Journal of Clinical Endocrinology & Metabolism. 44:884-891 |
| ISSN: | 1945-7197 0021-972X |
| DOI: | 10.1210/jcem-44-5-884 |
| Popis: | Eleven healthy male volunteers were infused with MSH/ACTH 4–10 and a control solution in a completely crossed and balanced procedure. Perception, attention and memory were tested as were heart rate and cephalic pulse amplitude in response to changes in the environment. Treatment of subjects with MSH/ACTH 4–10 raised their perceptual threshold for detection of simple stimuli and facilitated perceptual integration of patterned information. Administration of the heptapeptide improved the subjects' ability to discriminate tests of relevant from irrelevant information and augmented the heart–rate deceleratory response during presentation of novel stimuli. It was speculated that MSH/ACTH 4–10 has a predominant influence on attentional processes and that it may be uniquely coded for attentional/perceptual functioning. |
| Databáze: | OpenAIRE |
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