An expeditious one-pot synthesis of substituted phenylazetidin-2-ones in the presence of zeolite

Autor: Jyotsna S. Meshram, V. Udayini, Himani N. Chopde, Ramakanth Pagadala, Venkateshwarlu Jetti
Rok vydání: 2011
Předmět:
Zdroj: Journal of Heterocyclic Chemistry. 48:1067-1072
ISSN: 0022-152X
DOI: 10.1002/jhet.604
Popis: In this study, one-pot rapid and efficient series of phenylazetidin-2-ones were synthesized from N,N-dimethylaminobenzaldehyde, different substituted aromatic amines and phenylacetyl chloride in the presence of zeolite catalyst under microwave irradiation. We also reported schiff bases (1a–j) by classical and conventional microwave technique. The titled compounds are evaluated for their antimicrobial properties. The activities are due to CO, CN, linkages in 2-azetidinones. All the compounds have shown comparable antibacterial activities. J. Heterocyclic Chem., (2011).
Databáze: OpenAIRE