Amelanotic lentigo maligna melanoma: A diagnostic conundrum--Presentation of four new cases

Autor:	Darius R. Mehregan, Homayoon Rahbari, David A. Mehregan, Amir H. Mehregan, Hossein Nabai, Judith Lipinski
Rok vydání:	1996
Předmět:	Cancer Research medicine.medical_specialty business.industry Melanoma Cancer Lentigo maligna medicine.disease Dermatology Oncology medicine Histopathology Medical diagnosis Amelanotic melanoma Lentigo maligna melanoma business Pigmentation disorder
Zdroj:	Cancer. 77:2052-2057
ISSN:	1097-0142 0008-543X
DOI:	10.1002/(sici)1097-0142(19960515)77:10<2052::aid-cncr13>3.0.co;2-u
Popis:	BACKGROUND The clinical appearance of amelanotic lentigo maligna melanoma (ALMM) is quite confusing and usually is not diagnosed prior to histopathologic examination. METHODS We have studied four new patients with ALMM whose correct diagnosis was not obtained from any one clinical finding. We arrived at the final diagnosis in an unexpected way, having had biopsied the lesions for diagnoses other than malignant melanoma. RESULTS ALMM presents as a nonspecific skin lesion with no single indicative characteristic. A search of the literature confirmed our difficulty in making the diagnosis. CONCLUSIONS To diagnose ALMM, one has to be cognizant of this condition and has to consider a constellation of findings that are unusual with melanocytic lesions. Questionable lesions must be biopsied for definitive histopathologic diagnosis. Cancer 1996;77:2052-7.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::4bffeee5872e5b2a1d0bca2c033dbb77 https://doi.org/10.1002/(sici)1097-0142(19960515)77:10<2052::aid-cncr13>3.0.co Zobrazit plný text záznamu Plný text