Phytochemical Analysis and Antifungal Evaluation ofSebastiania commersoniana. Extracts

Autor:	Virginia Martino, Graciela Ferraro, Sabina Juárez, Oksana Hnatyszyn, Adriana Ouviña, Susana Zacchino
Rok vydání:	2007
Předmět:	Pharmacology biology Traditional medicine Pharmaceutical Science Microsporum gypseum General Medicine Trichophyton rubrum biology.organism_classification chemistry.chemical_compound Complementary and alternative medicine chemistry Phytochemical Scopoletin Drug Discovery Botany Caffeic acid Molecular Medicine Kaempferol Sebastiania Isorhamnetin
Zdroj:	Pharmaceutical Biology. 45:404-406
ISSN:	1744-5116 1388-0209
DOI:	10.1080/13880200701215216
Popis:	The 50% ethanol extract from Sebastiania commersoniana. (Baill.) L.B. Sm. & B.J. (Euphorbiaceae), a South American medicinal plant locally used as external antiseptic, was subjected to a phytochemical study and to the determination of its in vitro. antifungal activity. After fractionation of the extract, four flavonoids (quercetin, kaempferol, isorhamnetin, isoquercitrin), four phenolic derivatives (gallicin, gallic, syringic, and caffeic acids), and a coumarin (scopoletin) were identified. The structures of isolated compounds were established by spectroscopic methods and confirmed by comparison with reference samples and literature data. The extract exhibited significant antifungal activity against the dermatophytes Microsporum gypseum., Trichophyton mentagrophytes. and Trichophyton rubrum..
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::4bf7f17c59917d5e15b0067aa97146a0 https://doi.org/10.1080/13880200701215216 Zobrazit plný text záznamu Plný text ve formátu PDF Plný text ve formátu HTML
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