Synthesis, single crystal X-ray, spectroscopic characterization and biological activities of Mn2+, Co2+, Ni2+ and Fe3+ complexes
| Autor: | Azza A. Hassoon, Stacey J. Smith, Mohsen M. Mostafa, Roger G. Harrison, Nagwa Nawar |
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| Rok vydání: | 2020 |
| Předmět: |
Ionic radius
010405 organic chemistry Chemistry Organic Chemistry 010402 general chemistry 01 natural sciences 0104 chemical sciences Analytical Chemistry Ion Inorganic Chemistry Metal Crystallography chemistry.chemical_compound Thiourea visual_art Octahedral molecular geometry visual_art.visual_art_medium Ground state Single crystal Sodium acetate Spectroscopy |
| Zdroj: | Journal of Molecular Structure. 1203:127240 |
| ISSN: | 0022-2860 |
| DOI: | 10.1016/j.molstruc.2019.127240 |
| Popis: | A series of novel chloro-complexes of Mn2+, Co2+, Ni2+ and Fe3+ with 2,4,6-tris-(2-pyridyl)-1,3,5-triazine (L1) and thiourea (L2) with the formulae, [Mn(L1)Cl2(EtOH)]L2 (1), [Co(L1)Cl2(H2O)]L2.1/2H2O (2), [Ni(L1)Cl2(H2O)]L2.1/2H2O (3) and [Fe(L1)Cl3]L2 (4) were investigated utilizing convenient methods. Conversely, similar reaction resulted in complex with structure [Mn(L1)(OAc)(H2O)Cl]·H2O (5) in presence of sodium acetate. Pentagonal-bipyramidal geometry around Mn2+ ion is suggested. The solid state ESR spectra of Mn2+, Co2+ and Ni2+ complexes parameters show g|| > g┴ > 2.0023 indicating that the ground state is dx2-y2. Electronic spectra of two Mn2+ and the other complexes and the values of magnetic moments suggest octahedral geometry for complexes while pentagonal-pyramidal for [Mn(L1)Cl2(EtOH)]L2. Biological activity of complexes was tested versus alpathogenic bacteria (E. Coli, S. Aureus and C. Albicans). Further, the cytotoxic activity was screened for in vitro against (HeLa), (MCF-7), (HePG2) and (HeP-2). The role of ionic radii of the metal ion on the biological activity was investigated. |
| Databáze: | OpenAIRE |
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