Iron-Catalyzed Regioselective Decarboxylative Alkylation of Coumarins and Chromones with Alkyl Diacyl Peroxides

Autor:	Bin Sun, Can Jin, Xun Zhang, Tengwei Xu, Zhiyang Yan
Rok vydání:	2019
Předmět:	chemistry.chemical_classification 010405 organic chemistry Ligand Decarboxylation Iron catalyzed Organic Chemistry Regioselectivity Alkylation 010402 general chemistry 01 natural sciences 0104 chemical sciences chemistry Organic chemistry lipids (amino acids peptides and proteins) Alkyl
Zdroj:	Synlett. 30:1585-1591
ISSN:	1437-2096 0936-5214
DOI:	10.1055/s-0037-1611864
Popis:	A facile iron-catalyzed decarboxylative radical coupling of alkyl diacyl peroxides with coumarins or chromones has been developed, affording a highly efficient approach to synthesize a variety of α-alkylated coumarins and β-alkylated chromones. The reaction proceeded smoothly without adding any ligand or additive and provided the corresponding products containing a wide scope of functional groups in moderate to excellent yields. This protocol was highlighted by its high regioselectivity, readily available starting materials, and operational simplicity.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::4bca373a96ee7d7c0e5c321eb2d7edd8 https://doi.org/10.1055/s-0037-1611864 Zobrazit plný text záznamu