Asymmetric Rhodium-Catalysed Addition of Arylboronic Acids to Acyclic Unsaturated Esters Containing a Basic γ-Amino Group

Autor:	Elena Valverde, John Martin Pritchard, Allan J. B. Watson, Colin J. Suckling, Anderson Niall Andrew, Brendan J. Fallon, Simon J. F. Macdonald
Rok vydání:	2012
Předmět:	Butyric acid chemistry.chemical_compound chemistry Aryl Organic Chemistry Open-chain compound Enantioselective synthesis chemistry.chemical_element Organic chemistry Amine gas treating Enantiomeric excess Chemical synthesis Rhodium
Zdroj:	Synlett. 23:2817-2821
ISSN:	1437-2096 0936-5214
Popis:	Application of the Miyaura–Hayashi rhodium-catalysed addition of aryl boronic acids to acyclic unsaturated esters featuring basic centres to yield γ-amino butyric acids incorporating a substituted β-phenyl group is described. Unoptimised isolated yields and enantiomeric excesses vary from moderate to excellent, and the method tolerates a variety of substitution patterns and a range of functionality.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::4bb2337090fa7617f81ea4c4b6d28dea https://doi.org/10.1055/s-0032-1317512 Zobrazit plný text záznamu