Relationship between bone mineral density, coronary risk factors, C-reactive protein, and Insulin growth factor in frail elderly

Autor:	Hoda M. Farid, Tamer M. Farid, Heba G. Saber, Randa A. Mabrouk, Moatassem S. Amer
Rok vydání:	2014
Předmět:	Bone mineral medicine.medical_specialty biology business.industry Insulin medicine.medical_treatment Growth factor C-reactive protein Coronary risk factors Ocean Engineering University hospital Endocrinology Internal medicine medicine biology.protein Frail elderly business Lipoprotein
Zdroj:	Advances in Aging Research. :43-47
ISSN:	2169-0502 2169-0499
DOI:	10.4236/aar.2014.31008
Popis:	Objective: This study aimed to explore the relation between bone mineral density (BMD), inflammation, coronary risk factors, and Insulin growth factor (IGF) in frail elderly. Design: A casecontrol study. Setting: Ain Shams University Hospital Cairo, Egypt. Participants: Ninety aged 60 years and above; sixty frail (30 males and 30 females; mean age 70.03 ± 8.10) and thirty matched controls (15 males and 15 females; mean age 69.07 ± 5.93). Measurements: History, examination, comprehensive geriatric assessment, measurement of BMD, and laboratory investigations including; high sensitivity C-reactive protein (hs-CRP) glycated haemoglobin, IGF, lowdensity lipoprotein (LDL), high-density lipoprotein, total cholesterol, and triglycerides. Results: The frail group had significantly lower levels of triglycerides and LDL, hs-CRP and glycated haemoglobin levels were significantly higher (P Conclusion: Frailty was associated with low BMD, lower triglycerides & LDL levels, and higher hsCRP levels. A borderline significance was found between IGF levels and frailty. A positive correlation was found between BMD and IGF in frail.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::4bae38ca9c59485c6e4e4b8930f15a37 https://doi.org/10.4236/aar.2014.31008 Zobrazit plný text záznamu