Chemical Constituents of Metabolites Produced by the Actinomycete Acrocarpospora punica
| Autor: | Yen-Chen Cheng, Gwo-Fang Yuan, Ming Tsuen Hsieh, Ming-Jen Cheng, Hsun-Shuo Chang, Ih-Sheng Chen, Min Tseng |
|---|---|
| Rok vydání: | 2014 |
| Předmět: |
chemistry.chemical_classification
biology Lipopolysaccharide Stereochemistry Acrocarpospora Plant Science General Chemistry biology.organism_classification Aldehyde General Biochemistry Genetics and Molecular Biology Nitric oxide chemistry.chemical_compound chemistry Punica Fermentation Food science Quercetin Derivative (chemistry) |
| Zdroj: | Chemistry of Natural Compounds. 50:606-610 |
| ISSN: | 1573-8388 0009-3130 |
| DOI: | 10.1007/s10600-014-1034-5 |
| Popis: | One new γ-butyrolactone derivative, acrocarpunilactone (1), was isolated and identified from the rice solidsubstrate fermentation culture of an actinomycete, Acrocarpospora punica, together with nine known compounds, hydroxychavicol acetate (2), 4-allylcatechol (3), trans-caffeic aldehyde (4), (–)-ent-4β-hydroxy-10α-methoxyaromadendrane (5), (6α,7α)-4β-hydroxy-10α-methoxyaromadendrane (6), futoamide (7), N-[8′-(4′-hydroxyphenylethyl)]-2-hydroxybenzoylamide (8), hemiariensin (9), and 3-ethyl-4-hydroxybenzoic acid (10). Furthermore, the inhibitory effects of some isolates (compounds 1–6) on nitric oxide (NO) production in lipopolysaccharide (LPS)-activated macrophages were also evaluated. Compounds 1–3 showed stronger inhibition on NO production than the positive control quercetin. |
| Databáze: | OpenAIRE |
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