Abstract 11814: Pulmonary Capillary Wedge Pressure as a Strong Predictor for Successful Outcome of Atrial Fibrillation Ablation: A Speckle Tracking Echocardiographic Study
| Autor: | Mayumi Kaneda, Masanori Kawasaki, Takeshi Hirose, Ryuhei Tanaka, Rieko Matsuoka, Maki Nagaya, Kazuo Amano, Yoshiaki Goto, Shunichiro Warita, Shingo Minatoguchi, Tai Kojima, Koji Ono, Takatomo Watanabe, Shintaro Tanihata, Toshiyuki Noda, Sachiro Watanabe, Shinya Minatoguchi |
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| Rok vydání: | 2014 |
| Předmět: |
medicine.medical_specialty
business.industry medicine.medical_treatment Atrial fibrillation Speckle tracking echocardiography Ablation medicine.disease Pulmonary vein Left atrial Physiology (medical) Internal medicine medicine Cardiology Sinus rhythm Cardiology and Cardiovascular Medicine Pulmonary wedge pressure business Cardiac catheterization |
| Zdroj: | Circulation. 130 |
| ISSN: | 1524-4539 0009-7322 |
| DOI: | 10.1161/circ.130.suppl_2.11814 |
| Popis: | Background: Atrial fibrillation (AF) is associated with left atrial (LA) remodeling caused by LA pressure or volume (LAV) overload represented by the elevated left ventricular filling pressure or LA enlargement. Pulmonary capillary wedge pressure (PCWP) as well as LAV may be useful predictor for successful outcome of AF ablation. The aim of the study was to elucidate the most useful predictor for successful outcome in AF ablation including PCWP measured by a speckle tracking echocardiography (STE). Methods: We measured LAV, LA emptying function (EF), strain and strain rate (SR) by the STE during sinus rhythm before ablation in 137 patients with paroxysmal AF (61±10 years, 80 men) who underwent pulmonary vein isolation. The parameters were compared between non-recurrence (successful) group (n=107, age 61±11, sinus rhythm was continued for more than 1 year) and recurrence group (n=30, age 60±10). The estimated PCWP (ePCWP) was determined as 10.7 - 12.4 x log (active LAEF / minimum LAV), as we previously reported. LA stiffness was calculated as ePCWP/LA strain. We also measured PCWP and LA pressure by cardiac catheterization just before AF ablation in 59 patients. Results: The ePCWP was correlated with PCWP measured by cardiac catheterization (r=0.71, p Conclusion: Elevation of ePCWP before AF ablation was the best predictor of AF recurrence after AF ablation. This suggested a strong relation between LV filling pressure and the progression of LA remodeling responsible for AF. The ePCWP estimated by STE is useful to predict the successful outcome of AF ablation. |
| Databáze: | OpenAIRE |
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