Age-related effects of lead poisoning on sex hormones in adult male Wistar rats
| Autor: | A. B. Daku, A. B. El-ta’alu, A. I. Salisu |
|---|---|
| Rok vydání: | 2016 |
| Předmět: |
0301 basic medicine
medicine.medical_specialty 030102 biochemistry & molecular biology Adult male Environmental pollution Biology medicine.disease Lead poisoning 03 medical and health sciences 0302 clinical medicine Endocrinology Lead acetate 030220 oncology & carcinogenesis Internal medicine Age related medicine Ingestion Testosterone Hormone |
| Zdroj: | Journal of Physiology and Pathophysiology. 7:23-27 |
| ISSN: | 2141-260X |
| DOI: | 10.5897/jpap2015.0104 |
| Popis: | The World Health Organization (WHO) estimates that, about a quarter of the diseases facing mankind today occur due to prolonged exposure to environmental pollution, and that most of these environment-related diseases are however, not easily detected and may be acquired during childhood and manifested later in adulthood. The aim of this work was to determine the sub-chronic effects of lead poisoning on and some sex hormones, as well as age-related changes on Wistar Rats. Thirty (30) of 3-, 5-, and 7-months old age-groups male Wistar rats were selected; each age group was divided into experimental (lead fed) and control (distil water fed) groups. The levels of sex hormones (LH, FSH and Testestrone) were measured using ELISA method, while blood lead concentration was determined using the method of Atomic Absorption Spectrophotometer. There was a significant (P |
| Databáze: | OpenAIRE |
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