Comparison of Antithrombin III and Pentoxifylline Treatments in Gram Negative Sepsis Patients Developing DIC
| Autor: | Huseyin Oz, Guniz Meyanci Koksal, Mesure Gul Nihan Ozden |
|---|---|
| Rok vydání: | 2019 |
| Předmět: |
Disseminated intravascular coagulation
medicine.medical_specialty medicine.diagnostic_test business.industry Antithrombin Complete blood count Gram negative sepsis General Medicine Fibrinogen medicine.disease Gastroenterology Pentoxifylline Sepsis Internal medicine medicine Coagulation testing business medicine.drug |
| Zdroj: | Medeniyet Medical Journal. |
| ISSN: | 2149-2042 |
| DOI: | 10.5222/mmj.2019.05935 |
| Popis: | Objective The aim of this study was to evaluate the effects of antithrombin III (AT III) and pentoxifylline treatments on the gram negative septic patients with disseminated intravascular coagulation (DIC). Method For six days after plasma AT III activity dropped lower than 80% in Gram-patients who developed DIC were treated with AT III (90-120 IU/kg/day in 6 hours) or pentoxifylline (1.5 mg/kg/h in 6 hours) Fibrinogen, FDP, D-dimer, complete blood count, AT III activity, and DIC scores were calculated and recorded. Results The coagulation tests, AT III activity and FDP started to improve from the second day of treatment with both treatments (p |
| Databáze: | OpenAIRE |
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