Design, synthesis and evaluation of the Brigatinib analogues as potent inhibitors against tertiary EGFR mutants (EGFRdel19/T790M/C797S and EGFRL858R/T790M/C797S)

Autor:	Haotian Fang, Yingming Wu, Qitao Xiao, Dongbo He, Tongrui Zhou, Wenzhong Liu, Chun-Hao Yang, Yuli Xie
Rok vydání:	2022
Předmět:	Organic Chemistry Clinical Biochemistry Drug Discovery Pharmaceutical Science Molecular Medicine Molecular Biology Biochemistry
Zdroj:	Bioorganic & Medicinal Chemistry Letters. 72:128729
ISSN:	0960-894X
DOI:	10.1016/j.bmcl.2022.128729
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::4b42233244f70697e7655e9450ab1aca https://doi.org/10.1016/j.bmcl.2022.128729 Zobrazit plný text záznamu Full Text from ScienceDirect