Current Trends in Candidiasis
| Autor: | Priya Uppuluri, Afshin Khan, John E. Edwards |
|---|---|
| Rok vydání: | 2017 |
| Předmět: |
0301 basic medicine
medicine.medical_specialty business.industry Incidence (epidemiology) 030106 microbiology Disseminated Candidiasis medicine.disease 03 medical and health sciences 0302 clinical medicine Epidemiology medicine 030212 general & internal medicine Systemic candidiasis Gradual increase Bacterial vaginosis Intensive care medicine business Prosthetic heart Medical literature |
| Zdroj: | Candida albicans: Cellular and Molecular Biology ISBN: 9783319504087 |
| Popis: | In the 1940s, coincident with the introduction of antibacterial antibiotics into therapeutic strategies, a gradual increase in the number of reports of serious, deep organ candidal infections began to appear in the medical literature. Since then, there has been an abrupt increase in the incidence of hematogenously disseminated candidiasis and its complications. Candidiasis now represents the third-to-fourth most frequent nosocomial infection in hospitals in the US and worldwide. An important reason for this is that Candida species have a propensity to infect devices, and there has been a highly significant increase in the implantation of devices including indwelling catheters, artificial hips, knees and shoulders and prosthetic heart components, in recent years. The gravity of the situation deepens with the emergence of novel multidrug resistant species of Candida, such as C. auris, and the inability of existing diagnostic techniques to identify such species. Here, we discuss the current trends in the field of Candidiasis: epidemiology, most common or unusual clinical manifestations, and latest development in the areas of immunology and diagnostic testing. While this chapter is not meant to be exhaustive in content related to Candida, we have attempted to inform most recent updates in the field. |
| Databáze: | OpenAIRE |
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