Neofipiperzine D, A New Prenylated Indole Alkaloid metabolite of the Fungus Neosartorya Fischeri

Autor:	Jun-Lu Wang, Zha-Jun Zhan, Lu-Xi Jiang, You-Min Ying, Bing-Yu Chen, Zhen Wang, Wei Zhang
Rok vydání:	2014
Předmět:	Ergosterol Indole alkaloid biology Stereochemistry Alkaloid Metabolite General Chemistry Fungus biology.organism_classification Neosartorya fischeri Fumitremorgin C chemistry.chemical_compound chemistry Prenylation
Zdroj:	Journal of Chemical Research. 38:539-541
ISSN:	2047-6507 1747-5198
DOI:	10.3184/174751914x14097355956467
Popis:	A new prenylated indole alkaloid, neofipiperzine D, was isolated from the cultures of Neosartorya fischeri, together with three known metabolites fumitremorgin C, ergosterol, and ergosterol peroxide. The structure of the new compound was established by detailed analysis of its spectroscopic data, especially 1D, 2D NMR and HR-ESI-MS data. In an in vitro assay, neofipiperzine D did not exhibit any significant cytotoxicity against MCF-7, H1299, HUVEC, and MDA-MB-231 cell lines at a concentration of 20 μM.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::4b0bb75a6438d86822359a94300640bd https://doi.org/10.3184/174751914x14097355956467 Zobrazit plný text záznamu Plný text ve formátu PDF