| Popis: |
Background: The world is experiencing a pandemic caused by COVID-19, which has already led to the death of 3.5 million individuals. In this context, the scientific community has made several discoveries, above all, that COVID-19 can promote other disorders, in addition to respiratory, such as the impairment of the nervous system. Objectives: To analyze the main neurological changes resulting from the infection by COVID-19. Design and setting: Cross-sectional observational study. Methods: Literature review with articles published in 2020, in journals indexed in the PubMed and Scielo databases, using the descriptors “Neurologic Manifestations” AND “covid-19, including articles in Portuguese and English. Results: Neurological symptoms have become increasingly recurrent in patients with COVID-19. SARS-CoV-2 reaches the Central Nervous System (CNS) through hematogenous or retrograde neuronal dissemination. Peripheral neuropathies and cerebrovascular events are associated with the severity of the disease. The elevation of D-dimer in critically ill patients triggers cerebrovasculares events, especially the development of ischemic stroke (stroke), which becomes more evident due to its risk factors. Changes in mental status are not limited to severe cases, and can occur at any stage of the disease, especially neuropsychiatric syndromes, such as anxiety, depression and post- traumatic stress. Conclusion: COVID-19, in an advanced stage, promotes peripheral neuropathies and cerebrovascular events. Furthermore, regardless of the severity stage, it can lead to changes in mental status. |
