Diuretic-Associated Hypomagnesemia in the Elderly

Autor: Karen Milligan, Brendan J. Martin
Rok vydání: 1987
Předmět:
Zdroj: Archives of Internal Medicine. 147:1768
ISSN: 0003-9926
DOI: 10.1001/archinte.1987.00370100082014
Popis: • Serum magnesium concentration was measured in 320 consecutive elderly patients (mean age, 81 years) receiving diuretic therapy at the time of hospital admission. When compared with serum concentrations of 250 elderly patients who were not taking diuretics at the time of hospital admission, only the group taking thiazide diuretics had a significantly reduced mean serum level. The 24-hour urine sampling from representative subgroups demonstrated impaired magnesium-conserving ability in hypomagnesemic subjects receiving loop and thiazide diuretic therapy. Patients taking therapy that included a potassium-sparing diuretic had no significant evidence of reduced magnesium-conserving ability. Dietary assessments of the study population revealed suboptimal magnesium intake in the diet. (Arch Intern Med1987;147:1768-1771)
Databáze: OpenAIRE