Pulmonary function after COVID-19 in early convalescence phase
| Autor: | E. V. Kryukov, I. Ts. Kulagina, E. N. Kalmanova, M. V. Samsonova, Olga Savushkina, Alexander Cherniak, K. A. Zykov |
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| Rok vydání: | 2020 |
| Předmět: |
Spirometry
Lung medicine.diagnostic_test business.industry Convalescence media_common.quotation_subject respiratory system Pulmonary function testing 03 medical and health sciences FEV1/FVC ratio 0302 clinical medicine medicine.anatomical_structure 030228 respiratory system DLCO Diffusing capacity Concomitant medicine 030212 general & internal medicine Nuclear medicine business media_common |
| Zdroj: | Medical alphabet. :7-12 |
| ISSN: | 2078-5631 |
| Popis: | Pulmonary function after COVID-19 in early convalescence phase. The aim of the study is to investigate the influence of Coronavirus disease 2019 (COVID-19) on pulmonary function in early convalescence phase.Materials and methods. The study included 44 patients (35 male) after COVID-19 without concomitant bronchopulmonary pathology, with a median age of 47.5 years. All patients underwent standard pulmonary function tests (PFTs): spirometry, body plethysmography, diffusion test. Besides, dyspnea on the mMRC scale was assessed, oxygen saturation level (SpO2 ) was measured. Depending on degree of lung damage determined using high-resolution computed tomography (CT), the patients were divided into 2 groups: group 1 (22 patients) — CT 1 and CT 2, group 2 (22 patients) — CT 3 and CT 4.Results. The medians of standard PFTs parameters were in normal values. However, there were statistically significant differences between groups: VC, FVC, FEV1 and TLC were lower in second group. Diffusing capacity was reduced in 52% of patients. Statistical significant correlations were established between lung damage by CT and the parameters of VC, FVC, FEV1 , TLC, IC and DLCO.Conclusion. The degree of functional disorders of lungs depended on the extent of abnormal CT. Impaired diffusing capacity were detected in more than half of the COVID-19 patients in early convalescence phase. |
| Databáze: | OpenAIRE |
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