Abstract TMP3: Blood Pressure Variability Within 24 Hours After Mechanical Thrombectomy Correlates With Worse Outcome
| Autor: | Abhi Pandhi, Shareena Rahman, Ali Alawieh, Jan Liman, Mohammad Anadani, Akash P. Kansagra, Yser Orabi, Marios-Nikos Psychogios, Peter Kan, Shreyansh Shah, Fábio A. Nascimento, Ilko Maier, Andrei V Alexandrov, Stacey Q.Wolf, Hunter Mitchell, James A Giles, Ovais Inamullah, Nitin Goyal, Alejandro M Spiotta, Mohammad I Chaudry, Michelle Allen |
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| Rok vydání: | 2019 |
| Předmět: | |
| Zdroj: | Stroke. 50 |
| ISSN: | 1524-4628 0039-2499 |
| Popis: | Introduction: blood pressure variability (BPV) in the acute phase following ischemic stroke is associated with worse outcomes, especially in patients with large vessel occlusions. However, the relationship between BPV and outcome after successful recanalization is not well documented. Objective: The aim of this study was to evaluate the association between BPV and outcome after successful recanalization. Methods: This was a retrospective multicenter study of patients with anterior circulation large vessel occlusions who achieved successful recanalization with MT. Successful recanalization was defined as TICI≥2b. BP was recorded in hourly intervals for 24 hours post MT. BPV was defined as the difference between maximum and minimum blood pressure within 24 hours. BPV was calculated for mean arterial pressure (MAP), systolic BP (SBP), and diastolic BP (DBP). Outcome measures included 90 days mRS, symptomatic ICH (sICH), and mortality. sICH was defined based on ECASS criteria. Good outcome was defined as mRS 0-2. Results: A total of 985 patients were included. SBP and MAP variability were higher in poor outcome group (65.2±26 vs. 57± 24.6; p Conclusion: Higher blood pressure variability was associated with worse functional outcomes, higher likelihood of symptomatic hemorrhage, and increased mortality. |
| Databáze: | OpenAIRE |
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