Near-infrared spectroscopy carotid plaque characteristics and cerebral embolism in carotid artery stenting

Autor: Masashi Kotsugi, Hiroyuki Nakase, Takanori Furuta, Kaoru Myochin, Yasushi Motoyama, Fumiya Sato, Ichiro Nakagawa, Fumihiko Nishimura, Syuichi Yamada, Hun Soo Park
Rok vydání: 2021
Předmět:
Zdroj: EuroIntervention. 17:599-606
ISSN: 1774-024X
Popis: BACKGROUND Perioperative thromboembolism is the main consideration in carotid artery stenting (CAS). Precise evaluation of carotid plaque components is clinically important to reduce ischaemic complications since CAS mechanically pushes plaque outwards, which releases plaque debris into the bloodstream. AIMS This study aimed to determine whether high lipid core plaque (LCP) assessed by catheter-based near-infrared spectroscopy (NIRS) is associated with ipsilateral cerebral embolism by diffusion-weighted magnetic resonance imaging during CAS using a first-generation stent. METHODS Carotid stenosis magnetic resonance (MR) T1-weighted plaque signal intensity ratio (T1W-SIR) followed by NIRS assessment at the time of CAS (using the carotid artery Wallstent) was performed in 117 consecutive patients. RESULTS The maximum lipid core burden index (max-LCBI) at minimal luminal areas (MLA; max-LCBIMLA) and the max-LCBI for any 4 mm segment in a target lesion defined as max-LCBIarea were significantly higher for the post-procedural new ipsilateral diffusion-weighted magnetic resonance imaging (DWI)-positive than negative patients (p
Databáze: OpenAIRE