Diverging lesion and connectivity patterns influence early and late swallowing recovery after hemispheric stroke
| Autor: | Marian Galovic, Florian Brugger, Sjoerd B. Vos, Georg Kägi, Johannes Weber, Martin Zbinden, Manuela Pastore-Wapp, Natascha Leisi, Bruno Weder, Marlise Mueller |
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| Rok vydání: | 2017 |
| Předmět: |
0301 basic medicine
medicine.medical_specialty Lesion 03 medical and health sciences 0302 clinical medicine Swallowing Basal ganglia medicine Radiology Nuclear Medicine and imaging Stroke Enteral Tube Feeding Radiological and Ultrasound Technology medicine.diagnostic_test business.industry Magnetic resonance imaging medicine.disease Dysphagia Hyperintensity Surgery 030104 developmental biology Neurology Anesthesia Neurology (clinical) Anatomy medicine.symptom business 030217 neurology & neurosurgery |
| Zdroj: | Human Brain Mapping. 38:2165-2176 |
| ISSN: | 1065-9471 |
| Popis: | Knowledge about the recovery of oral intake after hemispheric stroke is important to guide therapeutic decisions, including the administration of enteral tube feeding and the choice of the appropriate feeding route. They aimed to determine the localization and connectivity of lesions in impaired recovery versus recovered swallowing after initially dysphagic stroke. Sixty-two acute ischemic hemispheric stroke patients with impaired oral intake were included in a prospective observational cohort study. Voxel-based lesion-symptom mapping and probabilistic tractography were used to determine the association of lesion location and connectivity with impaired recovery of oral intake ≥7 days (indication for early tube feeding) and ≥4 weeks (indication for percutaneous endoscopic gastrostomy feeding) after stroke. Two distinct patterns influencing recovery of swallowing were recognized. Firstly, impaired recovery of oral intake after ≥7 days was significantly associated with lesions of the superior corona radiata (65% of statistical map, P |
| Databáze: | OpenAIRE |
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