Synthesis of dialkyl and diaryl benzylphosphonates through a ZnI2-mediated reaction

Autor:	Rocky J. Barney, David F. Wiemer, Rebekah M. Richardson
Rok vydání:	2012
Předmět:	chemistry.chemical_compound chemistry Benzyl alcohol Zinc iodide Organic Chemistry Drug Discovery Organic chemistry Reactivity (chemistry) Biochemistry Phosphonate
Zdroj:	Tetrahedron Letters. 53:6682-6684
ISSN:	0040-4039
DOI:	10.1016/j.tetlet.2012.09.114
Popis:	Several trialkyl and two triaryl phosphites have been tested for their reactivity in the zinc iodide mediated conversion of benzyl alcohol to the corresponding phosphonates. Most react smoothly to afford the desired phosphonate diesters, including hindered and nonracemic phosphites. The implications of this reactivity on the reactions involved in the transformation are discussed.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::4a9cca523fd123f9bd42d64fb0f93766 https://doi.org/10.1016/j.tetlet.2012.09.114 Zobrazit plný text záznamu Full Text from ScienceDirect