A CASE OF BASALOID-SQUAMOUS CELL CARCINOMA OF THE ESOPHAGUS RESECTED AFTER CHEMOTHERAPY
| Autor: | Eiji Kurokawa, Yamamoto Shinji, Junichi Nishijima, Takahiko Tanigawa, Hitoshi Yamamoto, Hitoshi Ikegawa, Ichiro Fukuda, Keiji Iwanaga, Wakio Endoh |
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| Rok vydání: | 1998 |
| Předmět: | |
| Zdroj: | Nihon Rinsho Geka Gakkai Zasshi (Journal of Japan Surgical Association). 59:1536-1542 |
| ISSN: | 1882-5133 1345-2843 |
| DOI: | 10.3919/jjsa.59.1536 |
| Popis: | A 66-year-old man complaining of dysphagia was admitted to the hospital because he was pointed out having a whole-circumferential stenosis of the middle thoracic esophagus on double contrast radiography at another hospital. Histologic examination of biopsy specimens suggested an undifferentiated carcinoma of the esophagus. Since computed tomography showed a direct invasion of the tumor to the descending aorta and left main bronchus, the patient was treated with CDDP and 5 FU for 4 weeks before surgery. After the chemotherapy when the reduction rate of the tumor was 65%, an esophagectomy under left thoracotomy with reconstruction was conducted. The resected tumor was 6 × 3 cm in size, covered with normal moucosa. Histologic findings showed that cancer nests were consisted of small round cells and expanded downward with peripheral palisading arrangement and a hyaline basement-like matrix. Thus the diagnosis was made as basaloid cell carcinoma of the esophagus, with a stage-grouping of a2, n4, M0, P0, stage IV. Despite postoperative chemotherapy, the patient died of lung, liver, and lymph node metastases 14 months after the surgery. |
| Databáze: | OpenAIRE |
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